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doi: 10.3390/ijms22115495 98 HernndezMEMendietaDMartnez-FongDLoraFMorenoJEstradaIet al
IGF-1 is produced by the liver in response to GH stimulation and has a longer half-life than GH itself (~15 hours vs ~20 minutes), making it a more stable and reproducible measurement
Both peptides stimulate endogenous GH release, but their approved applications and clinical trial data reflect different therapeutic windows and patient populations
Both primary and secondary hypogonadism present with persistent low levels of testosterone, but primary hypogonadism is also associated with elevated luteinizing hormone (LH) while secondary hypogonadism may present with low or normal LH
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